This works with ALL areas, but only some spots are documented. So if you find a common pattern somewhere be sure to let us know in the forums and we'll add it here.
Heres some quick guides to get some of the common quests and runs without needing to resort to using maphack.
Nilithak
Once you nab the waypoint there are only three possible paths that you can take to get to the next level. Here they are:
Diablo 2 Maphack Plugy
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The action that actually triggers the portal to leave is nabbing the waypoint. However, I still say nab the waypoint. Why? Because without the waypoint, you will have far too long of a trip for these runs to be efficient...
To speed up finding Nihlathak in the final area, he will be in room opposite the room with the champions in the back. With this being said maximum rooms u will check are 3 and not four now.
Countess
There are 4 patterns
If you come out of the door and you can only move:
UP RIGHT, next level is UP LEFT
UP LEFT, next level is DOWN LEFT
DOWN RIGHT, next level is UP RIGHT
DOWN LEFT, next level is DOWN RIGHT
I don't mean upper left or downleft etc etc of map...Its the road leading to the top left/right etc.
General Observations
Another way to think of it is, in the hall or room you start out in, pretend you are in there yourself and looking towards the only direction that you can get out. now, simply follow the wall that is to the left of you
So always go to the left of which ever way the room or hall points to. More often then not it will be really close or diagonally across the map. This holds true with a lot of the 'underground' maps. Not always the case though. Heres some examples, the red arrow being the direction that the room points, green arrow being the left of the red arrow
Maphack was an illegal program in wide use by Diablo 2 players. Maphack allowed players to see the entire map as soon as they entered an area, rather than having to explore the area first to discover the layout of the level. Some versions of maphack would also show the location or full equipment of other players, as well as showing all of the monsters, shrines, chests, and more on the level.
The use of maphack violates the EULA and ToS, and numerous players have been suspended or banned from Battle.net for using it. Despite this, its use was (and is) quite common on the realms.
Diablo 2 Maphack
Purist players do not use maphack and tend to cheer on disciplinary actions taken against those who do. On the other hand, many players who use maphack argue that it's not 'really' cheating, since it just provides a sort of shortcut through boring levels they've already played a million times during their Diablo 2 career.
Diablo 3?[edit]
It's not known if or how Blizzard will attempt to prevent a Diablo 3 version of maphack from being put into use. Like all games, Diablo 3 must send the user's client more information than is seen on the screen, to save loading time and reduce lag. From this it's simple for programmers in the community to find ways to unlock that information and gain access to it before they could in the game. This means that programs like maphack are virtually impossible to stop, and a company can only work to detect and ban players who use them.